Used for SDS-PAGE
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq]
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-056551 |
| Réf. fabricant | 16101490 |
| À utiliser avec (application) | SDS-PAGE |
| Formule | In 50mM NH |
| Identification génétique (Entrez) | 348 |
| Poids moléculaire | 34kDa |
| Nom | APOE (Human) Native Protein |
| Méthode de préparation | Native protein purified from human plasma |
| Quantité | 50 ug |
| Conditions de stockage | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| État réglementaire | RUO |
| Alias de gène | AD2/LPG/MGC1571/apoprotein |
| Nom usuel | APOE |
| Symbole de gène(s) | APOE |
| Espèces | Human |
| Marqueur de protéine | None |
| Système d’expression | Native protein purified from human plasma |
| Forme | Liquid |
| Pureté ou qualité | ≥95% by SDS-PAGE |
