This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq]
Caractéristiques techniques
| Marque | Abnova |
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| Réf. B-LABO | BL-RE-056555 |
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| Réf. fabricant | 16028196 |
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| À utiliser avec (application) | Antibody Production, Conjugation, SDS-PAGE |
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| Formule | In 0.1M sodium phosphate buffer, 0.2M NaCl, pH 7.4 (0.09% sodium azide) |
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| Identification génétique (Entrez) | 174 |
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| Nom | AFP (Human) Native Protein |
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| Méthode de préparation | Native protein purified from human cord serum |
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| Quantité | 100 ug |
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| Conditions de stockage | Store at 4°C on dry atmosphere or store at -20°C for long term storage. After reconstitution, store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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| État réglementaire | RUO |
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| Alias de gène | FETA/HPAFP |
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| Nom usuel | AFP |
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| Symbole de gène(s) | AFP |
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| Espèces | Human |
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| Marqueur de protéine | None |
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| Système d’expression | Native protein purified from human cord serum |
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| Forme | Liquid |
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| Pureté ou qualité | ≥98% by SDS-PAGE |
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