Used for SDS-PAGE
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-056557 |
| Réf. fabricant | 16272170 |
| À utiliser avec (application) | SDS-PAGE |
| Formule | No additive |
| Identification génétique (Entrez) | 1277 |
| Nom | COL1A1 (Human) Native Protein |
| Méthode de préparation | Native protein purified from human tendon |
| Méthode de purification | Saltprecipitation/Ion Exchange Chromatography/Gelfiltration |
| Quantité | 1 mg |
| Conditions de stockage | Store at 4°C on dry atmosphere for short term storage. Store at -80°C for long term storage. Aliquot to avoid repeated freezing and thawing. |
| État réglementaire | RUO |
| Alias de gène | OI4 |
| Nom usuel | COL1A1 |
| Symbole de gène(s) | COL1A1 |
| Espèces | Human |
| Marqueur de protéine | None |
| Système d’expression | Native protein purified from human tendon |
| Forme | Lyophilized |
