Used for Func, SDS-PAGE
Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU; MIM 191840) and tissue plasminogen activator (PLAT; MIM 173370). The main function of plasmin is to dissolve fibrin (see, e.g., FGA, MIM 134820) clots. Plasmin, like trypsin, belongs to the family of serine proteinases (Miyata et al., 1982 [PubMed 6216475]; Forsgren et al., 1987 [PubMed 3030813]).[supplied by OMIM]
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-056570 |
| Réf. fabricant | 16068096 |
| Concentration | 4.1 mg/mL |
| À utiliser avec (application) | Functional Study, SDS-PAGE |
| Formule | In 0.1M Hepes, 0.1M NaCl, pH 7.4 |
| Identification génétique (Entrez) | 5340 |
| Poids moléculaire | 92kDa |
| Nom | PLG (Human) Native Protein |
| Méthode de préparation | Native protein purified from human plasma |
| Méthode de purification | Lysine sepharose chromatography |
| Quantité | 1 mg |
| Conditions de stockage | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| État réglementaire | RUO |
| Alias de gène | DKFZp779M0222 |
| Nom usuel | PLG |
| Symbole de gène(s) | PLG |
| Activité biologique | No plasmin activity is detected with chromogenic substrate S-2251.<br>> 98% conversion to plasmin is observed upon activation with uPA. |
| Espèces | Human |
| Marqueur de protéine | None |
| Système d’expression | Native protein purified from human plasma |
| Forme | Liquid |
