Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq]
Caractéristiques techniques
| Marque | Abnova |
| Réf. B-LABO | BL-RE-056612 |
| Réf. fabricant | 16262170 |
| Concentration | 2-4 mg/mL |
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| À utiliser avec (application) | SDS-PAGE |
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| Formule | Lyophilized from 50mM phosphate buffer, 100mM NaCl, 500μg glycine, pH 7.4 |
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| Identification génétique (Entrez) | 2 |
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| Poids moléculaire | 725kDa |
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| Nom | A2M (Human) Native Protein |
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| Méthode de préparation | Native protein purified from human blood |
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| Méthode de purification | Saltprecipitation/Chelate Chromatography/Gelfiltration |
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| Quantité | 1 mg |
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| Conditions de stockage | Store at -80°C. After reconstitution with deionized water, store at -80°C. Aliquot to avoid repeated freezing and thawing. |
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| État réglementaire | RUO |
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| Alias de gène | CPAMD5/DKFZp779B086/FWP007/S863-7 |
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| Nom usuel | A2M |
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| Symbole de gène(s) | A2M |
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| Espèces | Human |
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| Marqueur de protéine | None |
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| Système d’expression | Native protein purified from human blood |
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| Forme | Lyophilized |
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| Pureté ou qualité | >90% by SDS-PAGE |
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