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Used for Func, SDS-PAGE
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Numéro d’adhésion : P07858
À utiliser avec (application) : Functional Study, SDS-PAGE
Formule : In 50mM sodium acetate, 1mM EDTA, pH 5.0
Identification génétique (Entrez) : 1508
Nom : CTSB (Human) Native Protein
Méthode de préparation : Native protein purified from human liver
Quantité : 5 ug
Conditions de stockage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
État réglementaire : RUO
Alias de gène : APPS/CPSB
Nom usuel : CTSB
Symbole de gène(s) : CTSB
Activité biologique : 470 units/mg
Espèces : Human
Marqueur de protéine : None
Système d’expression : Native protein purified from human liver
Forme : Liquid
Pureté ou qualité : ≥95% by SDS-PAGE
