Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo
Davunetide is a highly potent active component of activity-dependent neuroprotective protein (ADNP). Prevents β-amyloid aggregation. Reduces hyperphosphorylated tau levels and increases tau-microtubule interactions; neuroprotective at femtomolar concentrations
in vitro
. Exerts neuroprotective effects in schizophrenia models associated with microtubule-autophagy insufficiency in MAP6-deficient mice. Modulates HIFs and VEGF expression and suppresses retinal cell apoptosis in an
diabetic retinopathy model.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-081529 |
| Réf. fabricant | 18797736 |
| Pureté | 95% |
| Contenu et stockage | Store at -20°C |
| Alias de gène | AL-108, NAP (peptide), NAPVSIPQ |
| Poids moléculaire | Observed: 824.93 |
| Quantité | 1 mg |
