Atosiban is a potent oxytocin receptor (OTR) antagonist. Inhibits oxytocin-induced increase in Ca2+ concentration in myometrial cells
in vitro
(IC50 = 5 nM) Activates NF-κB and MAPK pathways in human amnion via Gαi signaling, resulting in pro-inflammatory effects. Inhibits oxytocin-induced uterine contractions
in vivo
Caractéristiques techniques
| Marque | Tocris |
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| Réf. B-LABO | BL-RE-085271 |
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| Réf. fabricant | 18789836 |
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| CAS | 90779-69-4 |
|---|
| Contenu et stockage | Store at -20°C |
|---|
| Poids moléculaire | Observed MW: 994.19 |
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| Quantité | 10 mg |
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