Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq]
Caractéristiques techniques
| Marque | Abnova |
| Réf. B-LABO | BL-RE-086247 |
| Réf. fabricant | 16018046 |
| À utiliser avec (application) | SDS-PAGE, Western Blot |
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| Formule | No additive |
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| Identification génétique (Entrez) | 354 |
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| Poids moléculaire | 30kDa |
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| Nom | KLK3 (Human) Native Protein |
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| Méthode de préparation | Native protein purified from human seminal plasma |
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| Méthode de purification | Gel filtration/Ion exchange chromatography purification |
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| Quantité | 100 ug |
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| Conditions de stockage | Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
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| État réglementaire | RUO |
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| Alias de gène | APS/KLK2A1/PSA/hK3 |
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| Nom usuel | KLK3 |
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| Symbole de gène(s) | KLK3 |
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| Espèces | Human |
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| Marqueur de protéine | None |
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| Système d’expression | Native protein purified from human seminal plasma |
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| Forme | Lyophilized |
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| Pureté ou qualité | >95% by SDS-PAGE |
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