Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.
Caractéristiques techniques
| Marque | Novus Biologicals |
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| Réf. B-LABO | BL-RE-096338 |
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| Réf. fabricant | 18381624 |
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| Plage de dosage | 1.56 to 100 pg/mL |
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| Sensibilité du dosage | 0.94 pg/mL |
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| Type de produit | ELISA Kit (Colorimetric) |
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| Type d’échantillon | Plasma, Serum, Supernatant |
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| Spécificité | This kit recognizes Human GLP1 in samples. No significant cross reactivity or interference between Human GLP1 and analogues was observed |
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| À utiliser avec (application) | ELISA |
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| Identification génétique (Entrez) | 2641 |
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| Symbole de gène(s) | GCG |
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| Quantité | 1 Kit |
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| Disciplines de recherche | Cancer, Signal Transduction, Stem Cell Markers |
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| Conditions de stockage | Storage of components varies. See protocol for specific instructions. |
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| Synonyme | glicentin-related polypeptide, GLP1, glucagon-like peptide 1, GRPP |
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| Cible | Human |
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