Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-097402 |
| Réf. fabricant | 17899035 |
| Numéro d’adhésion | O15263 |
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| Type de produit | ELISA |
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| Identification génétique (Entrez) | 1673 |
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| Symbole de gène(s) | DEFB4A |
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| Quantité | 2 x 96 Tests |
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| État réglementaire | RUO |
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| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
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| Cible | Human |
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