ELISA
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-097403 |
| Réf. fabricant | 17899095 |
| Numéro d’adhésion | P35225 |
| Type de produit | ELISA |
| Identification génétique (Entrez) | 3596 |
| Symbole de gène(s) | Il13 |
| Quantité | 2 x 96 Tests |
| État réglementaire | RUO |
| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
| Cible | Human |
