This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.
Expression
SIRP gamma/CD172g
Numéro d’adhésion
XP_005568591
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
1177 bp
Marque
R&D Systems
Caractéristiques principales
Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a type I transmembrane protein belonging to the SIRP/SHPS (CD172) family within the Ig superfamily.
SIRP gamma is expressed on T cells, CD56bright NK cells and activated NK cells, but not myeloid cells.
Like SIRP alpha, it binds CD47, but unlike SIRP alpha, it does not contain an obvious signaling mechanism.
T cell SIRP gamma may play a role as an accessory protein interacting with CD47-expressing antigen presenting cells, and appears to promote antigen-specific T cell proliferation and costimulate T cell activation.
The SIRP gamma/CD172g insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
For reasearch use only. Not for use in humans.
Caractéristiques techniques
Marque
R&D Systems
Réf. B-LABO
BL-RE-099356
Réf. fabricant
18794779
Expression
SIRP gamma/CD172g
Numéro d’adhésion
XP_005568591
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
1177 bp
Identification génétique (Entrez)
55423
Alias de gène
bA77C3.1, CD172g, CD172g antigen, FLJ42230, signal-regulatory protein beta 2, Signal-regulatory protein beta-2, signal-regulatory protein gamma, SIRP beta 2, SIRP-b2, SIRPB2CD172 antigen-like family member B, SIRP-beta-2, SIRPG, SIRPgamma, SIRP-gamma
Contenu et stockage
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Espèces
Cynomolgus Monkey
Quantité
10 μg
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