This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.
Integrins are heterodimeric integral cell-surface proteins known to participate in cell adhesion as well as cellsurface mediated signaling, mediating interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM)
Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions
ITGAV undergoes posttranslational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins
ITGAV has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8
It is proposed that ITGAV may regulate angiogenesis and cancer progression
Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells
The Integrin alpha V/CD51 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided
For reasearch use only. Not for use in humans.
Caractéristiques techniques
Marque
R&D Systems
Réf. B-LABO
BL-RE-099708
Réf. fabricant
18732408
Expression
<i>cyno</i>ITGAV
Numéro d’adhésion
XP_005573729
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
3160 bp
Identification génétique (Entrez)
3685
Contenu et stockage
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Espèces
Cynomolgus Monkey
Quantité
10 μg
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