This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.
Expression
hTYROBP
Numéro d’adhésion
NP_003323
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
355 bp
Marque
R&D Systems
Caractéristiques principales
TYROBP TYRO protein tyrosine kinase binding protein [ Homo sapiens (human) ]
Also known as: DAP12; KARAP; PLOSL
The DAP12 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
DAP12 is a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain.
It may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element.
DAP12 may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation.
Alternatively spliced transcripts encoding different proteins have been described.
For reasearch use only. Not for use in humans.
Caractéristiques techniques
Marque
R&D Systems
Réf. B-LABO
BL-RE-099888
Réf. fabricant
18720208
Expression
<i>h</i>TYROBP
Numéro d’adhésion
NP_003323
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
355 bp
Identification génétique (Entrez)
7305
Contenu et stockage
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Espèces
Human
Quantité
10 μg
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