This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.
Expression
hMSR1
Numéro d’adhésion
NP_619729
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
1369 bp
Marque
R&D Systems
Caractéristiques principales
MSR1 macrophage scavenger receptor 1 [ Homo sapiens (human) ]
Also known as: SRA; SR-A; CD204; SRAI; phSR1; phSR2; SCARA1; SR-AII; SRAIII
The scavenger receptor (SR) family is a group of membrane receptors that share the common ability to bind and internalize modified forms of low-density lipoproteins (mLDL).
The three SR-A alternatively spliced isoforms (I, II, and III) and a structurally similar protein, MARCO, make up the A class of homotrimeric, type II membrane proteins.
SR-AI has an N-terminal cytoplasmic domain, transmembrane domain, spacer domain, a-helical coiled coil domain, collagen-like domain, and C-terminal cysteine-rich domain.
SR-As are expressed by most tissue macrophages and dendritic cells.
SR-As bind a broad range of polyanionic ligands and therefore have been implicated in many physiological and pathophysiological functions.
The SR-AI/MSR insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
For reasearch use only. Not for use in humans.
Caractéristiques techniques
Marque
R&D Systems
Réf. B-LABO
BL-RE-100198
Réf. fabricant
18791848
Expression
<i>h</i>MSR1
Numéro d’adhésion
NP_619729
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
1369 bp
Identification génétique (Entrez)
4481
Contenu et stockage
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Espèces
Human
Quantité
10 μg
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