Peptide antagonist of glucagon-like peptide-2 (GLP-2) receptor
GLP-2(3-33) is a peptide antagonist of glucagon-like peptide-2 (GLP-2) receptor. In cells, GLP-2(3-33) is generated by cleaving off the two N-terminal amino acids of GLP-2 with dipeptidylpeptidase IV (DPPIV). In high-fat diet (HFD) fed mice, GLP-2(3-33) treatment results in increased dyslipidemia and hepatic lipid accumulation. Chronic treatment of GLP-2(3-33) in HFD fed mice can cause hyperglycemia, glucose intolerance, high plasma insulin level after glucose load, increased pancreas weight and β-cell expansion.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-103964 |
| Réf. fabricant | 18715826 |
| Gene ID (Entrez) | 9340 |
| Pureté | 0.95 |
| CAS | 275801-62-2 |
| Contenu et stockage | Store at -20°C |
| Alias de gène | GLP-2 receptor, GLP-2 R, GLP-2-R, glucagon-like peptide 2 receptor |
| Poids moléculaire | M.W.-observed: 3557.93 |
| Quantité | 1 mg |
