Generated SQL Query: SELECT b.id, b.name, b.categoryId, b.subCategoryId FROM brand b GROUP BY b.id LIMIT 15
Tocris Bioscience™ LIH 383

Tocris Bioscience™ LIH 383

Ref: 30130458
159.82

Atypical chemokine receptor (ACKR3) agonist

Pureté:
0.95
CAS:
2866266-58-0
Contenu et stockage:
Store at -20°C
Poids moléculaire:
997.23
Quantité:
1 mg
Brand
Tocris Bioscience™

LIH 383 is a potent and highly selective atypical chemokine receptor (ACKR3/CXCR7) agonist. LIH 383 competes directly with CXCL12-AF647 and is more potent in inducing β-arrestin recruitment to ACKR3 (EC50 = 0.61 nM) than the full-length chemokine ligands CXCL12 or CXCL11 (EC50 = 1.2 nM and 2.2 nM, respectively). In a rat ex vivo model, LIH383 increases the availability and signaling of opioid peptides at classical receptors.

Pureté : 0.95


CAS : 2866266-58-0


Contenu et stockage : Store at -20°C


Poids moléculaire : 997.23


Quantité : 1 mg