Selective α7 nAChR antagonist
α-Bungarotoxin is a neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs). Prevents opening of nicotinic receptor-associated ion channels and is selective for α7 receptors over α3β4 receptors (IC50 values are 1.6 nM and > 3 μM respectively).
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-104220 |
| Réf. fabricant | 18715728 |
| Contenu et stockage | Store at -20°C |
| Poids moléculaire | 7984.14 |
| Type de produit | α-Bungarotoxin |
| Quantité | 1 mg |
| Séquence | Ile-Val-Cys-His-Thr-Thr-Ala-Thr-Ser-Pro-Ile-Ser-Ala-Val-Thr-Cys-Pro-Pro-Gly-Glu-Asn-Leu-Cys-Tyr-Arg-Lys-Met-Trp-Cys-Asp-Ala-Phe-Cys-Ser-Ser-Arg-Gly-Lys-Val-Val-Glu-Leu-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Ser-Lys-Lys-Pro-Tyr-Glu-Glu-Val-Thr-Cys-Cys-Ser-Thr-Asp-Lys-Cys-Asn-Pro-His-Pro-Lys-Gln-Arg-Pro-Gly (Disulfide bridges between 3 - 23, 16 - 44, 29 - 33, 48 - 59, 60 - 65) |
