des-His1-[Glu9]-Glucagon (1-29) amide is a glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release
in vitro
. Blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis
in vivo
Caractéristiques techniques
| Marque | Tocris Bioscience |
|---|
| Réf. B-LABO | BL-RE-104932 |
|---|
| Réf. fabricant | 18004092 |
|---|
| Pureté | 95% |
|---|
| Contenu et stockage | Store at -20°C |
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| Poids moléculaire | 3358.68 |
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| Type de produit | des-His<sup>1</sup>-[Glu<sup>9</sup>]-Glucagon (1-29) amide |
|---|
| Quantité | 1 mg |
|---|
| Séquence | Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2 |
|---|
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