This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-106420 |
| Réf. fabricant | 18077434 |
| Numéro d’adhésion | P11511 |
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| Plage de dosage | 0.16 to 10 ng/mL |
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| Sensibilité du dosage | 0.1 ng/mL |
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| Conjugué | HRP |
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| Type de produit | ELISA |
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| Type d’échantillon | Serum |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | 1588 |
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| Symbole de gène(s) | Cyp19a1 |
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| Coefficient de variation inter-dosage | <10% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer |
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| Marqueur ou colorant | HRP |
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| Quantité | 96 Tests |
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| État réglementaire | RUO |
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| Volume d’échantillon | 100 µL |
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| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
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| Cible | Human |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 3 hr 30 min |
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