Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Caractéristiques techniques
| Marque | Invitrogen |
| Réf. B-LABO | BL-RE-106421 |
| Réf. fabricant | 18077364 |
| Numéro d’adhésion | P10645 |
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| Plage de dosage | 62.5 to 4000 pg/mL |
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| Sensibilité du dosage | 37.5 pg/mL |
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| Conjugué | HRP |
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| Type de produit | ELISA |
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| Type d’échantillon | Serum |
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| À utiliser avec (équipement) | Colorimetric Microplate Reader |
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| Identification génétique (Entrez) | 1113 |
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| Symbole de gène(s) | Chga |
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| Coefficient de variation inter-dosage | <10% |
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| Coefficient de variation intra-dosage | <10% |
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| Contenus des kits | Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer |
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| Marqueur ou colorant | HRP |
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| Quantité | 96 Tests |
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| État réglementaire | RUO |
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| Volume d’échantillon | 100 µL |
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| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
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| Cible | Human |
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| Heure du test | 1 hr 20 min |
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| Durée totale du dosage | 3 hr 30 min |
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