ELISA
TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. It is expressed in heart, liver and prostate.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-106789 |
| Réf. fabricant | 17829085 |
| Numéro d’adhésion | Q969D9 |
| Type de produit | ELISA |
| Identification génétique (Entrez) | 85480 |
| Symbole de gène(s) | TSLP |
| Quantité | 10 x 96 Tests |
| État réglementaire | RUO |
| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
| Cible | Human |
