This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.
Expression
hLOXL1
Numéro d’adhésion
AAH68542
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
1738 bp
Marque
R&D Systems
Caractéristiques principales
Also known as: LOL; LOXL
LOXL1 is a member of the lysyl oxidase family of proteins.
It is essential to the biogenesis of connective tissue.
It is an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin.
A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function.
The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Mutations in LOXL1 are associated with exfoliation syndrome.
The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
For reasearch use only. Not for use in humans.
Caractéristiques techniques
Marque
R&D Systems
Réf. B-LABO
BL-RE-108876
Réf. fabricant
18719857
Expression
<i>h</i>LOXL1
Numéro d’adhésion
AAH68542
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
1738 bp
Identification génétique (Entrez)
4016
Contenu et stockage
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Espèces
Human
Quantité
10 μg
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