UCPH 101 is a selective non-substrate inhibitor of EAAT1 (IC50 values are 660, >300000 and >300000 nM for EAAT1, EAAT2 and EAAT3 respectively). Also demonstrates no significant inhibition at EAAT4 or EAAT5 in a patch-clamp electrophysiology assay (at final concentration up to 10 μM).
- Nom chimique ou matériau
- 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile
- CAS
- 1118460-77-7
- Quantité
- 10 mg
- Cible
- Glutamate (EAAT) Transporter Inhibitors
- Formule moléculaire
- C27H22N2O3
- Pureté
- 98%
