mSTING antagonist
C 176 is a mSTING antagonist. Covalently binds Cys91 of mouse but not human STING. Blocks activation-induced palmitoylation of STING and formation of STING clusters. Reduces CMA (Cat. No. 6677) -induced increase in serum IFNs
in vivo
and suppresses systemic inflammation in a mouse inflammatory disease model.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-124564 |
| Réf. fabricant | 18719486 |
| CAS | 314054-00-7 |
| Quantité | 10 mg |
| Cible | STING Antagonists |
| Formule moléculaire | C<sub>11</sub>H<sub>7</sub>IN<sub>2</sub>O<sub>4</sub> |
| Poids de la formule | 808 |
| Pureté | 97% |
