SERCA2 allosteric activator
CDN 1163 is a SERCA2 allosteric activator. Increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in
ob/ob
mice. Also improves glucose tolerance and reverses hepatic steatosis in
ob/ob
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-124756 |
| Réf. fabricant | 18711409 |
| Nom chimique ou matériau | 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide |
| CAS | 892711-75-0 |
| Quantité | 10 mg |
| Cible | Ca2+-ATPase Activators |
| Formule moléculaire | C<sub>20</sub>H<sub>20</sub>N<sub>2</sub>O<sub>2</sub> |
| Poids de la formule | 320.38 |
| Pureté | >98% |
