Photo-crosslinking probe for studying glycoproteins and glycolipids
Ac4ManNDAz is a cell-permeable photo-crosslinking probe for studying glycoprotein or glycolipid interactions. The compound is an unnatural diazirine-containing monosaccharide building block, which acts as a photo-crosslinker. Once inside the cell, Ac4ManNDAz is metabolized and incorporated into cell surface glycoproteins as a photo-crosslinking sialic acid analog. Upon UV irradiation, the diazirine group is activated to a reactive carbene that covalently crosslinks to nearby molecules.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-124844 |
| Réf. fabricant | 18779316 |
| Nom chimique ou matériau | 2-Deoxy-2-[[3-(3-methyl-3 H-diazirin-3-yl)-1-oxopropyl]amino]-D-mannopyranose-1,3,4,6-tetraacetate |
| CAS | 1015698-39-1 |
| Quantité | 10 mg |
| Cible | Photoactivatable Cross-linking Probes |
| Formule moléculaire | C<sub>19</sub>H<sub>27</sub>N<sub>3</sub>O<sub>10</sub> |
| Pureté | 0.98 |
