Functionalized cereblon ligand for PROTAC development
Phenyl-glutarimide 4'-oxyacetic acid is a carboxylic acid-functionalized cereblon ligand that can be used for PROTAC® Degrader development. The compound can be used to develop PG-PROTACs that exhibit improved stability to hydrolysis and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-124942 |
| Réf. fabricant | 18785796 |
| Nom chimique ou matériau | 2-(4-(2,6-Dioxopiperidin-3-yl)phenoxy)acetic acid |
| CAS | 2782024-58-0 |
| Quantité | 50 mg |
| Cible | Degrader Building Blocks |
| Formule moléculaire | C<sub>13</sub>H<sub>13</sub>NO<sub>5</sub> |
| Pureté | 0.95 |
