Sanguinarine chloride is an inhibitor of protein phosphatase 2C (PP2C), selective over PP1, PP2A and PP2B
in vitro
. Also inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) (IC50 = 10 μM). Plant alkaloid that exhibits anti-inflammatory and antioxidant activity. Blocks cell cycle in the G1 phase; inhibits cell growth in human prostate carcinoma cells.
Caractéristiques techniques
| Marque | Tocris |
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| Réf. B-LABO | BL-RE-124953 |
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| Réf. fabricant | 18726716 |
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| Nom chimique ou matériau | 13-Methyl-[1,3]-benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride |
|---|
| CAS | 5578-73-4 |
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| Plage de pourcentage du dosage | >97% |
|---|
| Quantité | 25 mg |
|---|
| Formule moléculaire | C<sub>20</sub>H<sub>14</sub>ClNO<sub>4</sub> |
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| Poids de la formule | Observed MW: 367.78 |
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