Fluoro functionalized Thalidomide; cereblon ligand for PROTACs
Thalidomide 5'- fluoro is a derivative of Thalidomide (Cat. No. 0652), commonly used as a precursor to PROTAC® Degraders that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a fluoro functional handle at a position known not to significantly affect binding to cereblon, ready for conjugation to a linker/target protein ligand.
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Require a different derivative? Get in touch .
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-124964 |
| Réf. fabricant | 18725356 |
| Nom chimique ou matériau | 2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-1 H-isoindole-1,3(2 H)-dione |
| CAS | 835616-61-0 |
| Quantité | 100 mg |
| Cible | Degrader Building Blocks |
| Formule moléculaire | C<sub>13</sub>H<sub>9</sub>FN<sub>2</sub>O<sub>4</sub> |
| Pureté | 0.95 |
