TRIM24 Degrader (PROTAC™)
Degrader (PROTAC®) composed of the TRIM24 ligand IACS-9571 conjugated to a VHL ligand. Displays dose- and time-dependent degradation of TRIM24 in cells, with maximum degradation achieved at 5 μM. Degradation phenotypically mirrors genetic deletion of TRIM24. Demonstrates antiproliferative effects in MOLM-13 cells. Cell permeable.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-124981 |
| Réf. fabricant | 18787006 |
| CAS | 2170695-14-2 |
| Quantité | 5 mg |
| Formule moléculaire | C<sub>55</sub>H<sub>68</sub>N<sub>8</sub>O<sub>13</sub>S<sub>2</sub> |
| Poids de la formule | 1113.3 |
| Type de produit | Degrader |
| Pureté | 98% |
