XMU MP 1 is a potent and selective ATP-competitive mammalian sterile 20-like kinase (MST) 1/2 inhibitor (IC50 values are 38.1 and 71.1 nM for MST2 and MST1, respectively). Enhances activity of downstream YAP
in vitro
. Augments mouse intestinal repair and promotes liver repair and regeneration in a mouse model of acute and chronic liver injury. Orally bioavailable.
Caractéristiques techniques
| Marque | Tocris |
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| Réf. B-LABO | BL-RE-125053 |
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| Réf. fabricant | 18787108 |
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| Nom chimique ou matériau | 4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide |
|---|
| CAS | 2061980-01-4 |
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| Quantité | 10 mg |
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| Formule moléculaire | C<sub>17</sub>H<sub>16</sub>N<sub>6</sub>O<sub>3</sub>S<sub>2</sub> |
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| Pureté | 98% |
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