SB 706504 is a p38 MAPK inhibitor. Inhibits LPS-induced transcription of a range of chemokines and cytokines in chronic obstructive pulmonary disease (COPD) monocyte derived macrophages (MDMs). Also inhibits LPS-induced protein expression of IL-6, IL-10, TNFα and γ-inducible protein 10 in COPD MDMs. Effects on suppression of LPS-induced gene and protein expression are enhanced in combination with dexamethasone (Cat. No. 1126).
Caractéristiques techniques
| Marque | Tocris Bioscience |
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| Réf. B-LABO | BL-RE-125103 |
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| Réf. fabricant | 18700799 |
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| Nom chimique ou matériau | N-Cyano-N'-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine |
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| CAS | 911110-38-8 |
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| Quantité | 10 mg |
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| Formule moléculaire | C<sub>24</sub>H<sub>19</sub>F<sub>3</sub>N<sub>8</sub>O |
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| Poids de la formule | 492.46 |
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| Pureté | 98% |
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