"/> Roscovitine | B-LABO France

Roscovitine

Réf. : BL-RE-125248Réf. fabricant : 18767506 10 mg
258,09 € HT

Potent, selective cyclin-dependent kinase inhibitor

CAS
186692-46-6
Synonyme
roscovitine, seliciclib, r-roscovitine, rosco, 2-r-1-ethyl-2-hydroxyethylamino-6-benzylamino-9-isopropylpurine, unii-0es1c2kq94, insolution™ roscovitine, chembl14762, bmk1-e12
Quantité
10 mg
Formule moléculaire
C19H26N6O
Marque
Tocris

Cyclin-dependent kinase (cdk) inhibitor. Displays sub-micromolar inhibition of cdk1, cdk2, cdk5, cdk7 and cdk9 (reported IC50 values range from 0.16 - 0.28 μM for cdk5 to 0.8 μM for cdk7). Selective for cdks over a wide range of related kinases including ERK1 and ERK2. Arrests L1210 cells in G1 phase. Inhibits phosphorylation of vimentin

in vivo

. Antimitotic.

Caractéristiques techniques

MarqueTocris
Réf. B-LABOBL-RE-125248
Réf. fabricant18767506
CAS186692-46-6
Synonymeroscovitine, seliciclib, r-roscovitine, rosco, 2-r-1-ethyl-2-hydroxyethylamino-6-benzylamino-9-isopropylpurine, unii-0es1c2kq94, insolution™ roscovitine, chembl14762, bmk1-e12
Quantité10 mg
Formule moléculaireC19H26N6O
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