TH 588 is a potent MTH1 inhibitor (IC50 = 5 nM). Induces oxidative DNA damage and reduces survival in cancer cells. Inhibits growth of breast and colorectal cancer xenografts in mice.
- Nom chimique ou matériau
- N4-Cyclopropyl-6-(2,3-dichlorophenyl)-2,4-pyrimidinediamine
- CAS
- 1609960-31-7
- Plage de pourcentage du dosage
- >98%
- Quantité
- 25 mg
- Formule moléculaire
- C13H12Cl2N4
- Poids de la formule
- Observed MW: 295.17
