MLN 4760 is a highly potent, cell-permeable and selective inhibitor of angiotensin converting enzyme 2 (ACE2) (IC50 = 0.44 nM). MLN 4760 inhibits production of angiotensin (1-7) from angiotensin II and reduces ACE2 expression and activity in an animal model of lung inflammation.
- Nom chimique ou matériau
- N-[(1 S)-1-Carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-L-histidine
- CAS
- 305335-31-3
- Quantité
- 2 mg
- Cible
- ACE Inhibitors
- Formule moléculaire
- C19H23Cl2N3O4
- Pureté
- 0.98
