Dopamine D3 receptor biased agonist
SK 609 is a dopamine D3 receptor biased agonist. Preferentially signals via the G protein-dependent pathway (EC50 values for G protein and β-arrestin-dependent signaling are 1.1 and 50.2 μM, respectively). Exhibits selectivity for D3 over D2 receptors. Improves motor deficits in rodent Parkinson's disease models and ameliorates L-DOPA (Cat. No. 3788) induced abnormal involuntary movements.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-125442 |
| Réf. fabricant | 18749446 |
| Nom chimique ou matériau | 2-chloro-α-methyl-benzenepropanamine hydrochloride |
| CAS | 1092797-77-7 |
| Quantité | 25 mg |
| Cible | Dopamine D3 Receptor Agonists |
| Formule moléculaire | C<sub>10</sub>H<sub>14</sub>ClN.HCl |
| Poids de la formule | 3333 |
| Pureté | 98% |
