Fluorescent probe that selectively identifies undifferentiated iPS/ES cells
Kyoto Probe-1 or KP-1 distinguishes between undifferentiated iPS/ES cells and differentiated cells, so may be used for monitoring pluripotency during hESC or iPSC maintenance. Kyoto Probe 1 distinguishes between SSEA-4-positive hESCs and human early hematopoietic cells expressing CD45, CD235, CD41a, or CD43 in flow cytometry experiments, making it a valuable tool for studying early hematopoiesis. The product also distinguishes between hiPSCs and hiPSC-derived cardiomyocytes. Note that Kyoto Probe 1 does not differentiate between hiPSCs and differentiated human neuronal stem cells.
Kyoto Probe 1 localizes to the mitochondria in undifferentiated iPS/ES cells only. Suitable in flow cytometry and live cell imaging.
Excitation maximum = 515 nm; emission maximum = 529 nm; Quantum yield = 0.45
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-125565 |
| Réf. fabricant | 18758146 |
| Nom chimique ou matériau | 9-(4-Fluorophenyl)-3-imino-3 H-xanthen-6-amine trifluoroacetate |
| CAS | 2088021-81-0 |
| Quantité | 100 μg |
| Cible | Compounds for ESC/iPSC Proliferation and Renewal |
| Formule moléculaire | C<sub>19</sub>H<sub>13</sub>FN<sub>2</sub>O.CF<sub>3</sub>CO<sub>2</sub>H |
| Pureté | 0.95 |
