Selective PARP-10 inhibitor
OUL 35 is a selective PARP-10 (also known as ADP-ribosyltransferase Diptheria Toxin-like 10, ARTD10) inhibitor (IC50 = 0.329 μM). Displays selectivity for PARP-10 over a panel of PARP family members. Rescues HeLa cells from PARP-10-induced cell death. Sensitizes cancer cells to hydroxyurea-induced genotoxic stress.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-125587 |
| Réf. fabricant | 18074412 |
| CAS | 6336-34-1 |
| Synonyme | 4,4′-Oxybis[benzamide] |
| Quantité | 5 mg |
| Formule moléculaire | C<sub>14</sub>H<sub>12</sub>N<sub>2</sub>O<sub>3</sub> |
| Poids de la formule | 256.26 |
| Pureté | 98% |
