WQ 1 is a high affinity and selective σ1 receptor antagonist (pKi values are 10.28-10.85, 5.81-6.53 and 5.80 at σ1, σ2 and DAT). Displays σ1/σ2 selectivity ratio of 29512. Selectively blocks binge eating without a general inhibition of food intake in rats.
- Nom chimique ou matériau
- 2,3-Dihydro-2-[1-(phenylmethyl)-4-piperidinyl]-4 H-1-benzothiopyran-4-one
- CAS
- 1204401-49-9
- Quantité
- 50 mg
- Cible
- Sigma1 Receptor Antagonists
- Formule moléculaire
- C21H23NOS
- Pureté
- 0.98
