Opioid receptor (KOR) agonist
Helianorphin-19 is a high affinity, potent and selective κ-opioid receptor (KOR) agonist (Ki = 25 nM; EC50 = 45 nM). Helianorphin-19 exhibits approximately 200-fold selectivity for KOR over μ and δ-opioid receptors.
In vivo
Helianorphin-19 shows potent peripheral analgesic efficacy in a mouse model of visceral pain without affecting motor coordination/sedation.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-125699 |
| Réf. fabricant | 18745716 |
| Quantité | 1 mg |
| Cible | Kappa Opioid Receptor Agonists |
| Formule moléculaire | C<sub>81</sub>H<sub>132</sub>N<sub>26</sub>O<sub>16</sub>S<sub>2</sub> |
| Pureté | 0.95 |
