Nrf2 activator
Oltipraz is a Nrf2 activator; activates Nrf, which binds to antioxidant response elements (AREs) and induces Phase-I and -II drug-metabolizing enzymes including CYP2B and NQO1. Also increases mRNA levels of multiple hepatic xenobiotic transporters. Elevates expression of genes encoding anti-oxidant and multidrug resistance-associated proteins. Displays chemopreventive activity.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-126016 |
| Réf. fabricant | 18756009 |
| Nom chimique ou matériau | 4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione |
| CAS | 64224-21-1 |
| Quantité | 10 mg |
| Cible | Nrf2 Modulators |
| Formule moléculaire | C<sub>8</sub>H<sub>6</sub>N<sub>2</sub>S<sub>3</sub> |
| Poids de la formule | 226.34 |
| Pureté | >99% |
