DSR 6434 is a potent TLR7 agonist (EC50 = 7.2 nM). Activates several immune effector cells in vitro. Suppresses metastasis in vivo and enhances efficacy of radiation therapy in a model of colorectal carcinoma.
- Nom chimique ou matériau
- DSR 6434
- CAS
- 1059070-10-8
- Synonyme
- 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one
- Quantité
- 50 mg
- Solubilité
- Soluble to 50mM in 1eq. HCl and to 100mM in DMSO
- Formule moléculaire
- C19H28N8O2
- Poids de la formule
- 400.48
- Forme physique
- Solid
- Type de produit
- Bioactive Small Molecule
- Pureté
- >98%
