p38 MAPK inhibitor
SB 706504 is a p38 MAPK inhibitor. Inhibits LPS-induced transcription of a range of chemokines and cytokines in chronic obstructive pulmonary disease (COPD) monocyte derived macrophages (MDMs). Also inhibits LPS-induced protein expression of IL-6, IL-10, TNFα and γ-inducible protein 10 in COPD MDMs. Effects on suppression of LPS-induced gene and protein expression are enhanced in combination with dexamethasone (Cat. No. 1126).
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-126142 |
| Réf. fabricant | 18726258 |
| Nom chimique ou matériau | N-Cyano-N′-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine |
| CAS | 911110-38-8 |
| Quantité | 50 mg |
| Cible | p38 Inhibitors |
| Formule moléculaire | C<sub>24</sub>H<sub>19</sub>F<sub>3</sub>N<sub>8</sub>O |
| Poids de la formule | 492.46 |
| Pureté | >98% |
