TREK1 and TREK2 channel activator
GI 530159 is a TREK1 and TREK2 channel activator (EC50 = 0.76 μM in Rb efflux assay in TREK1-expressing CHO cells). Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane potential of dorsal root ganglion neurons and depresses neuronal activity
in vitro
.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-126259 |
| Réf. fabricant | 18775826 |
| Quantité | 50 mg |
| Formule moléculaire | C<sub>27</sub>H<sub>20</sub>F<sub>6</sub>N<sub>2</sub>O<sub>2</sub> |
| Poids de la formule | 518.45 |
| Type de produit | Channel Activator |
| Pureté | 99% |
