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Tocris Bioscience™ Chlorhydrate de BI dihydrochloride BI hydrochloride BI

Réf. : BL-RE-126322Réf. fabricant : 18777616 10 mg
397,40 € HT

DFHBI derivative for imaging of RNA in living cells that bind Broccoli aptamers

Nom chimique ou matériau
(5 Z)-3-(1 H-Benzimidazol-7-ylmethyl)-5-[(3,5-difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-4 H-imidazol-4-one dihydrochloride
Quantité
10 mg
Cible
Light-up Aptamers
Formule moléculaire
C19H14F2N4O20.2 HCl
Pureté
0.98
Marque
Tocris Bioscience

BI is a DFHBI derivative for imaging of RNA in cells. BI increases brightness and photostability of Broccoli aptamers in cells. BI enables imaging of single Broccoli-tagged mRNAs in living cells. BI exhibits peak excitation of 470 nm and peak fluorescence emission of 505 nm when bound to Broccoli. BI exhibits higher affinity for Broccoli aptamers and a 10.5-fold increase in cellular fluorescence compared with DFHBI-1T (Cat. No. 5610) (KD values are 51 and 305 nM, respectively).

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-126322
Réf. fabricant18777616
Nom chimique ou matériau(5 Z)-3-(1 H-Benzimidazol-7-ylmethyl)-5-[(3,5-difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-4 H-imidazol-4-one dihydrochloride
Quantité10 mg
CibleLight-up Aptamers
Formule moléculaireC<sub>19</sub>H<sub>14</sub>F<sub>2</sub>N<sub>4</sub>O<sub>2</sub>0.2 HCl
Pureté0.98
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