Activin/BMP/TGFβ pathway inhibitor; Inhibits ALK4, ALK5, and ALK7
Synonyme
SB-431542
Quantité
1 mg
Formule moléculaire
C22H16N4O3 · XH2O
Pureté
≥98%
Marque
STEMCELL Technologies
SB431542 is a selective and potent inhibitor of the TGF-β/Activin/NODAL pathway that inhibits ALK5 (IC50 = 94 nM), ALK4 (IC50 = 140 nM), and ALK7 by competing for the ATP binding site
It does not inhibit the BMP type I receptors ALK2, ALK3, and ALK6
This product is supplied as the hydrate form of the molecule
