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STEMCELL Technologies Purmorphamine | B-LABO France
STEMCELL Technologies Purmorphamine
Réf. : BL-RE-126440Réf. fabricant : 17120042 1 mg
97,20 € HT
Hedgehog pathway activator; Activates Smoothened
CAS
483367-10-8
Quantité
1 mg
Formule moléculaire
C31H32N6O2
Pureté
≥98%
Marque
STEMCELL Technologies
Caractéristiques principales
Purmorphamine is a tri-substituted purine derivative that activates the Hedgehog pathway by directly binding to and activating the Hedgehog receptor Smoothened (EC50 = 1 μM)
(Sinha and Chen)
Promotes differentiation of ventral spinal progenitors and motor neurons from human pluripotent stem cells (Hu and Zhang, Karumbayaram et al.), Li et al.)
Promotes differentiation of osteoblasts from human and mouse mesenchymal cells (Beloti et al.), Wu et al. 2002, Wu et al.) 2004)
Inhibits differentiation and maturation of adipocytes from human mesenchymal cells (Fontaine et al.)
