(-)-Epigallocatechin Gallate is the most abundant polyphenol catechin antioxidant present in green tea (Frémont et al.; Johnson & Maddipati; Miller & Rice-Evans) and is known to inhibit DNA methyltransferases (DNMTs; IC50 = 0.21 - 0.47 μM; Lee et al.) (-)-Epigallocatechin Gallate also inhibits the formation of oxidized low-density lipoproteins (Yoshida et al.), which have a pathological role in cardiovascular diseases and atherosclerosis (Itabe et al.) (-)-Epigallocatechin Gallate has also been shown to inhibit peroxynitrite-mediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine (Fiala et al.)
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-126456
Réf. fabricant
17160252
CAS
989-51-5
Synonyme
EGCG; NVP-XAA723; Tea catechin
Quantité
50 mg
Formule moléculaire
C<sub>22</sub>H<sub>18</sub>O<sub>11</sub>
Pureté
≥98%
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